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Simultaneous Segmentation, Kinetic Parameter Estimation, and Uncertainty Visualization of Dynamic PET Images

Abstract

We develop a segmentation technique for dynamic PET incorporating the physiological parameters for different regions via kinetic modeling. We demonstrate the usefulness of our technique on fifteen [11C]Raclopride simulated PET images.We show qualitatively and quantitatively that the physiologically based algorithm outperforms two classical segmentation techniques. Further, we derive a formula to compute and visualize the uncertainty encountered during the segmentation.

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Authors
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Supplemental Material
Citation
Category
Paper in Conference Proceedings or in Workshop Proceedings (Full Paper in Proceedings)
Event Title
Medical Image Computing and Computer-Assisted Intervention (MICCAI), 2007
Divisions
Visualization and Data Analysis
Subjects
Computergraphik
Event Location
Brisbane, Australia
Event Type
Conference
Event Dates
November 2007
Date
November 2007
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